Paul S. Charifson,Michael P. Clark,Upul K. Bandarage,Randy S. Bethiel,Michael J. Boyd,loana Davies,Hongbo Deng,John P. Duffy,Luc J. Farmer,Huai Gao,Wenxin Gu,Joseph M. Kennedy,Brian Ledford,Mark W. Le
申请号:
US15177546
公开号:
US20160355512A1
申请日:
2016.06.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I):or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.