A knee prosthesis system for total knee replacement procedures includes a plurality of distinctly-sized femoral components (10,20), a plurality of distinctly-sized fixed tibial components (70), a plurality of distinctly-sized mobile tibial components (80), a plurality of fixed inserts (30,50), and a plurality of mobile inserts (40,60). Each of the mobile inserts is sized and shaped such that each may be optimally matched to one of the femoral components and may be used with any one of the mobile tibial components. Each of the fixed inserts is sized and shaped such that each may be optimally matched to one of the femoral components and may be used with any one of the fixed tibial components.