A drill guide for guiding elements, especially drill bits and implants of an implantation kit during a surgical intervention, has a main body having a gripping portion. The drill guide has an upper and a lower central opening along its longitudinal axis with a through going cavity for receiving the element to be guided. A lower contact surface is positioned on an object, such as a bone, on or into which the element is to be guided. The diameter of the through going cavity can be varied by a.) radial positioning of three or four jaws inside the cavity through a groove-slide block system and/or b.) against the force of a spring at the lower free end of guiding extensions. The spring is provided on the back side of the extensions which bear against the inner wall of the drill guide sleeve.