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Administration of lorcaserin to individuals with renal impairment
专利权人:
Arena Pharmaceuticals; Inc.
发明人:
Anderson, Christen M.,Shanahan, William R.
申请号:
AU2016200860
公开号:
AU2016200860B2
申请日:
2016.02.10
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2016200860B220171012.pdf#####ABSTRACT OF THE DISCLOSURE The present disclosure relates to methods for weight management in an individual in need thereof by 5 determining the level of renal sufficiency of the individual and prescribing or administering a therapeutically effective amount of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof to the individual, provided that the individual has a level of renal sufficiency selected from the group consisting of: no renal impairment, mild renal impairment, and moderate renal impairment. In addition, the disclosure relates to a method 10 for selecting an individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof from a plurality of individuals in need of weight management by determining the level of renal sufficiency of the individual and selecting the individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof if the individual 15 has a level of renal sufficiency selected from the group consisting of: no renal impairment, mild renal impairment, and moderate renal impairment.
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