Gunnar Nordvall;Johan Bylund;Maria E Ek;Ylva Gravenfors;Jenny Viklund;Jörg Holenz;Alexander Minidis;Karl S. A Vallin;Stefan Von Berg;Daniel Sohn
发明人:
Johan Bylund,Maria E Ek,Ylva Gravenfors,Gunnar Nordvall,Alexander Minidis,Karl S. A Vallin,Jenny Viklund,Jörg Holenz,Stefan Von Berg,Daniel Sohn
申请号:
US12747049
公开号:
US09145380B2
申请日:
2008.12.18
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides compounds of formula (I) wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.