University of Washington through its Center for Commercialization
发明人:
David W. Russell,Roli K. Hirata
申请号:
US16507589
公开号:
US20190381154A1
申请日:
2019.07.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides isolated primate cells preferably human cells that comprise a genetically engineered disruption in a beta-2 microglobulin (B2M) gene, which results in deficiency in MHC class I expression and function. Also provided are the method of using the cells for transplantation and treating a disease condition.