Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino) -1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3- carboxylic acid in combination therapy
Methods of treating, preventing or managing cancers are disclosed. The methodsencompass the administration of SNS-595 in combination with a second activeagent. In certain embodiments, the method of treatment comprise administeringSNS-595 in combination with cisplatin, carboplatin, gemcitabine or a combinationthereof.