Methods for reducing intra-ocular pressure and for treating eye disorders characterized by increased intra-ocular pressure, such as glaucoma, by ophthalmic administration of a pharmaceutical composition comprising a pyrethroid compound that is lambda-cyhalothrin or an analog thereof through topical administration of the composition or incorporation into an intraocular device. Pharmaceutical compositions for the treatment of such eye disorders comprising lambda-cyhalothrin or an analog thereof and methods for making them are disclosed.