<;P>;PROBLEM TO BE SOLVED: To provide a method for developing a new revascularization method by transplanting endothelial cells obtained by differentiating/proliferating from a VPC and VPC derived from embryonic stem cells. <;P>;SOLUTION: This method for differentiating and proliferating the endothelial cells, especially arterial endothelial cells efficiently is provided by elevating the cAMP concentration in vascular endothelial proliferation factor receptor Flk-1 positive cells differentiated from the embryonic stem cells by using adrenomedullin, etc. <;P>;COPYRIGHT: (C)2005,JPO&NCIPI