A neural probe incorporating optical waveguide is disclosed. The neural probe includes a substrate, a plurality of electrode parts and an optical waveguide. The electrode parts are disposed on a first surface of the substrate. The optical waveguide is connected with the first surface or the second surface of the substrate.本新型公開一種神經探針,其包括一基板、多個電極部以及一光波導。各電極部分別設置基板的第一面。其中,光波導與基板的第一面或基板的相對第一面的第二面相互結合。