A computer-implemented method for non-invasively identifying ablation locations in atrial tissue, can include: receiving three-dimensional imaging data representing atrial tissue of a left atrial flutter (LAFL) subject； generating a subject-specific model of the at least one of the atrial tissue from the three-dimensional imaging data； estimating tissue fiber orientations in the atrial tissue； assigning the estimated tissue fiber orientations to the subject-specific model of the atrial tissue； conducting simulations of LAFL using the subject-specific model to identify regions of slow conduction of a propagating wave within an atrial tissue region of the atrial tissue； a critical isthmus of a rotational wavefront within the atrial tissue region； or a region based on a minimum cut in a flow network； and identifying at least one ablation location in the atrial tissue region based on the identified regions of slow conduction, the critical isthmus, or the minimum cut.
