PROBLEM TO BE SOLVED: To provide a film-form preparation which, in desensitization therapy, enables a patient to self-administer an allergen and adjust the dose, has excellent portability, has no residual sensation, provides excellent protection against accidental swallowing, is easy for a caregiver to administer, and can greatly improve the QOL of both patients and caregivers and additionally, enables arbitrary control of the dissolution time in the mouth, particularly sublingually and has very little sticky sensation in the mouth and better feeling when touched by the fingers and to provide a method for producing the film-form preparation.SOLUTION: The film-form preparation comprises an allergen, an edible polymer which is soluble in both water and a polar organic solvent, and one, two or more types of particles selected from the group consisting of monosaccharide to hexasaccharide sugars and sugar alcohols thereof which have an average particle size of 0.1 to 100 &mum.COPYRIGHT: (C)2011,JPO&INPIT【課題】減感作療法において、患者がアレルゲンの自己投与、投与量の調整が可能で、携帯性にも優れ、残渣感がなく誤飲防止性にも優れ、介護者が投与しやすく、患者及び介護者のQOLを大幅に向上させることができ、更に、口腔内、特に舌下における溶解時間を任意に制御することができるとともに、口腔内におけるネバネバ感が低減され、指で触った際の触感を向上させることができるフィルム状製剤、及び、該フィルム状製剤の製造方法を提供すること。【解決手段】アレルゲンと、水及び極性有機溶媒に可溶性である可食性高分子と、平均粒子径が0.1~100μmである単糖~六糖の糖及びこれらの糖アルコールからなる群より選ばれる1種又は2種以上の粒子とを含有するフィルム状製剤。【選択図】図1
