Li, Yuncheng,Jiang, Tao,Pei, Wei,Marsilje III, Thomas H.,Michellys, Pierre-Yves,Huang, Chen,Wu, Baogen,Chen, Bei,Gao, Zhaobo,Ge, Yonghui,Nguyen, Truc Ngoc,Zhu, Xuefeng
申请号:
AU2009233964
公开号:
AU2009233964B2
申请日:
2009.04.03
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof.