STABLE COMPOSITION (OPTIONS), MEDICINES (OPTIONS) AND METHODS FOR TREATMENT AND PREVENTION OF SKIN INFECTIONS AND INFECTIONS OF SKIN STRUCTURES, DISEASES, TRANSFERS
ГУЛЬЕТТА Антонио (IT),РАГА Мануэль (ES),САНТОС Бенхамин (ES),ТАРРАГО Кристина (ES)
申请号：
RU2011119764/15
公开号：
RU2011119764A
申请日:
2009.10.16
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A stable composition in the form of a cream for topical application, comprising 0.2 ÷ 5 wt.% Ozenoxacin and a suitable carrier, containing: 15 ÷ 25 wt.% At least one emulsifier selected from the group comprising ethylene glycol monostearate, sorbitan tristearate, mixtures of PEG6 stearate, glycol stearate and PEG32 stearate, hydrogenated lecithin and mixtures thereof； 10 ÷ 20 wt.% of at least one surfactant selected from the group consisting of monoolein / propylene glycol sorbitolate, C / fatty acid mono- and diglycerides from coconut oil s eu lecithin, egg phosphatides, esters of citric acid and monoglycerides, esters of lactic acid and monoglycerides, esters of diacetyl tartaric acid and monoglycerides, esters of succinic acid and monoglycerides, esters of sucrose and fatty acids, polyglycolized glycerides of oleic acid, polyglycolized glycerides of oleic oleic acid acids, polyglycerol esters of fatty acids and polyglyceryl esters of mixed fatty acids and mixtures thereof； 5-15% by weight of the oil component which is present is Gerbeh alcohol (2-octyldodecanol)； 1 ÷ 10 wt.% at least one wax with a low melting point selected from the group consisting of fatty alcohols with 8-30 carbon atoms and mixtures thereof； 10 ÷ 20 wt.% at least one water-dispersible component selected from the group consisting of PEG400, hexylene glycol, propylene glycol, methyl glucose ether and polypropylene glycol 10, ethoxy glycol, PEG 6 caprylic / capric glycerides, ethylene glycol monobutyl ether, caprylic 3-glycolides, caprylic 3-glycerides, methyl 1-boo1. Стабильная композиция в виде крема для местного применения, включающая 0,2÷5 мас.% озеноксацина и подходящий носитель, содержащий:15÷25 мас.% по меньшей мере одного эмульгатора, выбранного из группы, включающей этиленгликоль моностеарата, сорбитан тристеарата, смеси ПЭГ6 стеарата, гликольстеарата и ПЭГ32 стеарата, гидрированный лецитин и их смеси；10÷20 мас.% по меньшей мере одного поверхностно-активного вещества, выбранного из г
