Xinzhan Peng,Xinshe Xu,Daniel R. Draney,Garrick M. Little,Jiyan Chen,William M. Volcheck,Charles Prescott
申请号:
US11423675
公开号:
US08227621B2
申请日:
2006.06.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides for cyanine dyes as near IR quenchers. The cyanine dyes have absorption wavelengths in the near-infrared region of about 650-900 nm and are essentially non-fluorescent. The dyes of the invention have at least one linking group. The present invention also provides substantially non-fluorescent, NIR probes. Biological assays based on these novel, substantially non-fluorescent, NIR probes are also provided.