LIN, SHIMING,林世明,林世明,LEE, CHIH KUNG,李世光,李世光,LEE, ADAM SHIH YUAN,李世元,李世元,HONG, JIM TONG,洪锦堂,洪錦堂,CHENG, MING CHU,郑明珠,鄭明珠,LIN, CHIH CHEN,林志成,林志成,WU, RONG SIN,吴荣信,吳榮信,CHU, SHU FANG,朱淑芳,朱淑芳,CHANG, YU TING
申请号：
TW098123749
公开号：
TWI488661B
申请日:
2009.07.14
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
A method for breaking down virus/bacteria and to suppress their infection and proliferation by using 2-(10-mercaptodecyl) malonic acid or salts thereof is provided. A method for synthesizing 2-(10-mercaptodecyl)malonic acid, comprising reacting ethyl 2-(10-bromo-decyl)malonate with thiourea and ethanol, and then with aqueous sodium hydroxide is also provided.本發明提供一種廣效性崩解抑制病毒細菌感染增殖之物質及其相關方法,包括使用2-(10-氫硫基癸基)丙二酸(2-(10-mercaptodecyl)malonic acid)或其鹽類,特別是抑制(1)有套膜流感病毒及(2)無套膜腸病毒與(3)葡萄球菌感染之方法。本發明亦提供一種2-(10-氫硫基癸基)丙二酸之製造方法,包括使2-(10-溴癸基)丙二酸乙酯(ethyl 2-(10-bromo-decyl)malonate)與硫脲(thiourea)及乙醇反應後,再與NaOH水溶液反應。
