Chimeric antigen receptors based on single-domain antibodies and methods of use thereof

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专利权人:

Legend Biotech Ireland Limited

发明人:

Fan, Xiaohu,Chou, Chuan-Chu,Zhuang, Qiuchuan,Wang, Pingyan,Wang, Lin,Yang, Lei,Hao, Jiaying

申请号：

AU2016305075

公开号：

AU2016305075A1

申请日:

2016.08.10

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present application provides single-domain antibodies, and chimeric antigen receptors comprising one or more antigen binding domains each comprising a single-domain antibody. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/