Nazim El-Andaloussi,Antonio Marchini,Jean Rommelaere,Barbara Leuchs,Max Endele
申请号:
US13627554
公开号:
US09803219B2
申请日:
2012.09.26
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described is an adenovirus derived helper virus which may comprise the adenoviral DNA sequences for E2a, S4 (orf6), the VA1 RNA gene, and the parvovirus VP capsid gene unit. Also described is a method of efficiently preparing a recombinant parvovirus (particle) which is based on the use of various adenoviral derived helper viruses/vectors.