Methods of therapy with anti-CD154 antibodies having impaired FcR binding and/or complement binding properties

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专利权人:

THE TRUSTEES OF DARTMOUTH COLLEGE

发明人:

Randolph J. Noelle

申请号：

US13648808

公开号：

US09321833B2

申请日:

2012.10.10

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Improved anti-CD154 antibodies are provided herein which have ablated FcR binding and/or complement binding/activation. The use of these antibodies for inducing tolerance and treating immune diseases including autoimmunity, inflammation and allergic disorders is disclosed herein.

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中国工程科技知识中心

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http://www.ckcest.cn/home/