The present invention relates to a peptide inhibiting a matrix metalloproteanases activity and use thereof. The peptide inhibiting a matrix metalloproteanases activity exhibits an excellent efficacy of improving the condition of skin by directly inhibiting the matrix metalloproteanases activity. In addition a composition containing the peptide of the invention has excellent bioactivities of inhibiting the activity of hyaluronic acid degrading enzymes adipogenesis in fat cells angiogenesis and the like thereby being useful for the treatment of various diseases such as anti obesity anti cancer anti inflammation and the like and skin permeability is excellent due to the small size of the peptide thereby being useful in various fields. The peptide of the invention having excellent activity and safety can be advantageously applied to drugs quasi drugs and cosmetics.
