An intra-cavity circulation heat perfusion apparatus, comprising a casing (100), an electromagnetic induction heating means, and a controller. The electromagnetic induction heating means comprises a tray and an electromagnetic induction coil; the tray is used for bearing a heating tank (410); a master control unit of the controller controls the electromagnetic induction coil to be electrified to heat the heating tank (410), so as to indirectly heat a medicinal liquid in a liquid storage chamber (410a); a data acquisition unit is used for acquiring medicinal liquid temperature values of the heating tank (410), a liquid outlet pipeline (102), and a liquid return pipeline (104) and transferring same to the master control unit; the master control unit controls a power control unit according to the medicinal liquid temperature values to control a heating power of the electromagnetic induction coil. After reaching a predetermined temperature, the temperature of the medicinal liquid maintains constant. Since a medicinal liquid is heated to a predetermined temperature before being introduced into bladder for treatment, the medicinal liquid can fully exert a thermal destruction mechanism after being introduced into bladder, so as to kill and wound metastatic cancer cells extensively grown on serosa to eliminate a lesion that causes malignant effusion, reach the purpose of effectively treating cancer effusion, and effectively improve the treatment effect.