KIM, NAM HO,LEE, JIN YOUNG,KIM, JAE-SUN,LEE, NAM KYU,JANG, WOO JAE,OH, JOON GYO,LEE, YOON-JUNG,KIM, WOONG SIK,SUNG, JIN-HEUNG,UM, KEY AN
申请号：
CA2653124
公开号：
CA2653124C
申请日:
2007.05.22
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to a stable pharmaceutical composition forinjectioncontaining docetaxel and a method of preparing the same. More particularly,the presentinvention relates to a pharmaceutical composition for injection containingdocetaxel havingbetter storage stability than conventional medications, which is prepared bydissolving docetaxel,a water-insoluble compound, in distilled water after mixing it withcyclodextrin (CD) and awater-soluble polymer such as hydroxypropyl methylcellulose (HPMC),polyethylene glycol (PEG) orpolyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method ofpreparing the same.
