ADURO BIOTECH, INC.;PROVIDENCE HEALTH & SERVICES - OREGON D/B/A PROVID ENCE PORTLAND MEDICAL CENTER
发明人:
Peter M. Lauer,Keith Bahjat
申请号:
US15722908
公开号:
US20180021420A1
申请日:
2017.10.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.