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Levodopa spray
专利权人:
DIZLIN PHARMACEUTICALS AB
发明人:
BRING, LEIF,EHRNEBO, MATS,DIZDAR SEGRELL, NIL,ERIKSSON, ELIAS
申请号:
ARP180101500
公开号:
AR112070A1
申请日:
2018.06.05
申请国别(地区):
AR
年份:
2019
代理人:
摘要:
Water solution (SNC) for the treatment of central nervous system diseases,The dissolved levodopa contains at least 5 mg / ml of solution with a pH range of 3.0 to 8.5. This solution is provided by two mixtures: (a) a standard aqueous solution including levodopa, a typical solution with a standard pH less than 2.8-25 ℃; and (b) an underwater Seine solution to raise the pH of the standard solution to at least 4.0-25 ℃. It is used to treat patients with central nervous system diseases immediately after mixing the main aqueous solution and the underwater purse seine solution. Besides,It provides a set of prescriptions for patients with central nervous system diseases. 1. Requirement 1: aqueous solution for the treatment of central nervous system diseases;Aqueous formulations, including at least 5 mg / ml dissolved levodopa, with a pH range of 3.0 to 8.5, are provided by mixing; (a) a main aqueous solution including levodopa, and a main aqueous solution with a pH range of 2.8 to 25 ℃; and (b) an aqueous self-service solution for Increase the pH value of this standard solution, including at least one buffer component, i.e. a pH value of at least 4.0 to 25 ℃, and apply the aqueous solution to the subjects suffering from central nervous system diseases within 24 hours, such as 16 hours, 12 hours and 6 hours,4 hours, 2 hours, 1 hour, 30 minutes, 20 minutes, 10 minutes, 5 minutes or 1 minute from the mixing of the aqueous main solution and the underwater scarf solution. 109. Claim 59: a set of aqueous solution medicine packs for the treatment of central nervous system diseases;According to any of the above requirements, the dissolved levodopa prescription shall contain at least 5 mg / ml of aqueous solution with pH value between 3.0 and 8.5, including: (a) the standard aqueous solution containing levodopa according to any of the above requirements, The pH value of this water mode solution is 2.8-25 ℃ (b) the water sample purse seine solution meeting any of the above requireme
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