A device suitable for use in a body lumen comprises an elongated control member and a radially expansible cage disposed at or adjacent to a distal end of the elongated control arm that is adjustable between a contracted orientation and an expanded (deployed) orientation The radially expansible cage is adapted to scrape thrombus from vessel walls, or collect matter removed from vessel walls, when in a deployed orientation. The device comprises an extractor comprising a helical formation adapted to rotate, and wherein the helical formation has a variable pitch along its length.
