Consejo Superior De Investigaciones Científicas (CSIC)
发明人:
申请号：
EP17382028.3
公开号：
EP3351291A1
申请日:
2017.01.20
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
A device for electrically stimulating living cells and promoting biological cell growth and differentiation is hereby disclosed, said device being based on the generation of an electrical field due to a piezoelectric effect yielded by a nanostructure made from a piezoelectric material. When a cell contacts the nanostructure, the nanostructure suffers a mechanical stress which in turn produces an electrical field that locally stimulates the cell membrane. This in-situ electrical stimulation allows the activation of voltage-dependent ionic channels present in the membrane of electroconductive cells. It allows the control of key cellular messengers, such as calcium ions, that can lead to the stimulation of neural circuits in neurons, provoking motion in muscle cells or promoting cell growth and differentiation.
