Provided are methods of improving the cardiac condition of post-myocardial infarction (MI) patients and reducing cardiovascular death and hospitalization due to heart failure or arrhythmias, by administering a therapeutically effective amount of an A2B adenosine receptor antagonist.本發明提供經由投服治療上有效量之A2B腺苷受體拮抗劑來改善心肌梗塞(MI)後之病患內的心臟病況並減少因心衰竭或心律不整而造成之心血管死亡及住院的方法。