Alexandre Mikhailovitch Nesterov;Sandip K. Nandy;Jiyun Liu;Carmen Hertel;Abeysinghe A. Padmapriya
发明人:
Sandip K. Nandy,Jiyun Liu,Alexandre Mikhailovitch Nesterov,Carmen Hertel,Abeysinghe A. Padmapriya
申请号:
US12506497
公开号:
US08362305B2
申请日:
2009.07.21
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.