ANNETT ROZEK;SOLIGENIX INC.;SHANNON WAYNE LENTZ;INIMEX PHARMACEUTICALS INC.;OREOLA DONINI
发明人:
OREOLA DONINI,ANNETT ROZEK,SHANNON WAYNE LENTZ
申请号：
IL19060108
公开号：
IL190601A
申请日:
2008.04.03
申请国别(地区):
IL
年份:
2014
代理人:
摘要：
In one aspect, the present invention provides isolated novel peptides that can be used to modulate innate immunity in a subject. and/or for the treatment of an immune-related disorder, including treating and preventing infection by modulating innate immunity. Also provided are an agent reactive with the peptide, a pharmaceutical composition that includes the peptide, an isolated nucleic acid molecule encoding the peptide, a recombinant nucleic acid construct that includes the nucleic acid molecule, at least one host cell comprising the recombinant nucleic acid construct, and a method of producing the peptide using the host cell. The present invention further provides a method for treating and/or preventing infection in a subject by administering the peptide of the invention to the subject, thereby modulating innate immunity in the subject. Additionally, the present invention provides a method for predicting whether a subject would be responsive to treatment with a peptide of the invention.
