INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
发明人:
CHOI, Yeung-Joon,최영준
申请号：
KRKR2013/007557
公开号：
WO2014/030950A1
申请日:
2013.08.23
申请国别(地区):
WO
年份:
2014
代理人:
摘要：
The present invention relates to oyster hydrolysate-derived novel peptides having the effects of inhibiting the activity of collagenase, to a pharmaceutical composition comprising the novel peptides as active ingredients for preventing or treating collagenase-mediated diseases, to a functional health food comprising the novel peptides as active ingredients for preventing or improving collagenase-mediated diseases, and to an anti-wrinkle cosmetic composition comprising the novel peptides as active ingredients. The novel peptides according to the present invention may effectively inhibit the activity of collagenase, and therefore the composition comprising the novel peptides of the present invention as active ingredients can be effectively used not only in the prevention, improvement or treatment of collagenase-mediated diseases, but also in reducing wrinkles. Thus, the novel peptides of the present invention can be widely used as a material for various fields such as the drug industry, food industry and cosmetic industry. Particularly, the novel peptides of the present invention are based on the amino acid sequence of the peptides derived from a natural product, and may be safe without exhibiting cytotoxicity. Therefore, the composition of the present invention comprising the novel peptides as active ingredients may have the advantage of being safe over a long period of use.La présente invention concerne de nouveaux peptides dérivés dun hydrolysat dhuître présentant des effets dinhibition de lactivité dune collagénase, une composition pharmaceutique comprenant les nouveaux peptides utilisés comme principes actifs et destinée à prévenir ou à traiter des maladies médiées par une collagénase, un aliment naturel fonctionnel comprenant les nouveaux peptides utilisés comme principes actifs et destiné à prévenir ou à soulager des maladies médiées par une collagénase, et une composition cosmétique anti-rides comprenant les nouveaux peptides utilisés comme principes actifs. L
