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咪唑並吡啶化合物
专利权人:
Astellas Pharma Inc
发明人:
Toshio, KUROSAKI,Tsubasa WATANABE,Kazuhiko OHNE,Hiroki ISHIOKA,Eisuke NOZAWA,Takeshi HANAZAWA,Shunichiro HACHIYA,Hiroshi SHIBATA,Yuji KOGA,Ryo MIZOGUCHI
申请号:
HK16101051.6
公开号:
HK1212984A
申请日:
2016.01.29
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
[Problem] A pharmaceutical composition for treating or preventing various cardiovascular diseases, which have sGC activities based on improvement of cGMP signals, is provided. [Means for Solution] It was found that imidazo[1,2-a]pyridine compounds having a carbamoyl group at the 3-position and a particular cyclic group at the 8-position via a methyleneoxy group, or a salt thereof have sGC activation, and are useful as active ingredients of pharmaceutical compositions for treating or preventing various sGC-related cardiovascular diseases, in particular, peripheral arterial diseases, intermittent claudication, critical limb ischemia, hypertension, and pulmonary hypertension, thereby completing the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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