ANTIBODY AND ANTIGEN RECOGNIZING TUMOR-INITIATING CELLS AND USE THEREOF

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专利权人:

BEIJING INSTITUTE FOR CANCER RESEARCH

发明人:

ZHANG, ZHIQIAN,ZHAO, WEI,WANG, LIMIN,HAN, HAIBO,XING, BAOCAI

申请号：

EP12749191

公开号：

EP2682475A4

申请日:

2012.02.22

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

Disclosed is a method for searching, identifying, or validating a marker CACNA2D1 of tumor-initiating cells. The method comprises a step of immunizing an animal using HEP-12 cells originating from a recurrent tumor and rich in originating cells. Also disclosed is a monoclonal antibody specially recognizing CACNA2D 1 or antigen-binding fragments thereof, and the use thereof for treating or preventing tumors or diseases or conditions related to CACNA2D1.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/