SIEVERS, ERIC,KENNEDY, DANA,IHLE, NATHAN,SUN, MICHAEL
申请号:
EP10729571
公开号:
EP2376110A4
申请日:
2010.01.08
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Methods for the treatment of CD30-expressing cancers are provided. The methods comprise administering to a subject in need thereof a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an antibody-drug conjugate compound having formula (I) or a pharmaceutically acceptable salt thereof wherein: mAb is an anti-CD30 antibody unit, S is a sulfur atom of the antibody, A- is a Stretcher unit, and p is from about 3 to about 5.