Methods for the Prevention, reduction or elimination of the incidence of diseases or symptoms of androgen deficiency in men include Symptoms or Diseases associated with male hypogonadism associated with low levels of Serum testosterone and / or Low DHEA levels or B Garlic total levels of androgens likely in warm blooded Animals, including humans,Which involves the Administration of a quantity of a precursor of Sex steroids, dehydroepiandrosterone (DHEA), and in particular a Selective Estrogen Receptor Modulator (SERM) (in particular acolbifene), an antiestrogen or a prodrug of the two.The symptoms or diseases are loss of libido, Erectile Dysfunction, fatigue, loss of Energy, depression, bone loss, Muscle loss, Fat accumulation, Muscle weakness, loss of Memory, loss of Cognition, dementia, Alzheimer's disease, loss of body weight L, fertility problems, gynecomastia, anemia, insomnia, hot flashes, sweating,Decreased sense of well-being, obesity, osteoporosis, hyperlipidemia, Hypercholesterolemia, atherosclerosis, hypertension, insulin resistance, cardiovascular disease and type 2 diabetes. Also disclosed are Pharmaceutical compositions for the Administration of the active ingredients and set (S) components that are useful for this.Claim 20: a Pharmaceutical composition for preventing, reducing or Eliminating the incidence of diseases or symptoms of androgen deficiency in men include Symptoms or Diseases associated with male hypogonadism as defined in claim 1, characterized P Because a component, comprises: (a)Pharmaceutically acceptable diluent or Carrier； b) at least one precursor of Sex steroid or prodrug thereof as defined in claim 4； and (c) at least one Selective Estrogen Receptor Modulator or a prodrug of antiestrogen or any of them as Defined in any of Claims 6 to 11 and 13； where this is prov Pharmaceutical compositionEE in a container that manages the use of said composition for the Prevention, reduction or elimination of at least a symptom or disease Male a
