Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
发明人:
Yeaman, Michael R.
申请号:
HK18112987
公开号:
HK1253854A1
申请日:
2018.10.11
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
Antimicrobial peptides, compositions and methods are described that are useful for treating infectious diseases, including those caused by drug resistant Gram-negative bacteria (e.g., Pseudomonas and Acinetobacter) and parasite-caused diseases such as malaria. The peptides include a modular kinocidin gamma-core connected directly, or through a short spacer, to a kinocidin C-terminal alpha-helix.