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Fast disintegrating preparation containing calcium carbonate
专利权人:
株式会社三和化学研究所
发明人:
日比野 恒之,近藤 真弘,足立 圭助,落合 直也,佐藤 勇二
申请号:
JP2010516874
公开号:
JP5490691B2
申请日:
2009.06.11
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
Disclosed is a technique for producing a rapidly disintegrating preparation which contains calcium carbonate, can rapidly disintegrate with a small quantity of water or saliva in the oral cavity and has such tablet physical properties that can fully withstand the conditions for market distribution in a rotary compression molding machine without the need of employing any complicated process or any specialized production facility. Specifically disclosed is a rapidly disintegrating preparation containing calcium carbonate, which is shaped by the direct tableting of a material comprising at least the components (A) and (B) shown below in a compression molding machine, has a tablet hardness of 40 to 200 N, has a tablet wear rate of 1% or less, and requires 60 seconds or shorter for the disintegration in the oral cavity. (A) Calcium carbonate having a 50% particle diameter of 20 to 100 µm as measured on the powder particle size by a laser diffraction method. (B) A component which can increase the moldability of the whole preparation when mixed with calcium carbonate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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