BURRIESCI, Gaetano,RAHMANI, Benyamin,BYRNE, Guerard,MCGREGOR, Christopher
申请号：
GBGB2017/052073
公开号：
WO2018/011592A1
申请日:
2017.07.13
申请国别(地区):
GB
年份:
2018
代理人:
摘要：
A bioprosthetic heart valve and the method for fabricating said bioprosthetic heart valve； the method comprising: providing: a sheet of biological tissue (11)； a sheet of a biocompatible material (2), and a stent (4), the stent (4) having an upstream edge (41) and a downstream edge (42) as well as an inner surface and an outer surface； attaching the biological tissue (11) to the biocompatible material (2) along a suture line (3)； folding the biocompatible material to form a tubular structure with the attached biological tissue located on the inner surface of the tubular structure, the biological tissue forming the leaflets (11) of the heart valve； securing the stent around the outer surface of the tubular structure such that the tubular structure extends in an upstream direction beyond the upstream edge of the stent and in a downstream direction beyond the downstream edge of the stent； cutting at least one region of the biocompatible material at the downstream end of the tubular structure； folding the biocompatible material at the cut region away from the biological tissue and around the downstream edge of the stent and securing it to the outer surface of the stent； and folding the biocompatible material at the upstream end of the tubular structure around the upstream edge of the stent and attaching to the outer surface of the stent so that the inner and outer surfaces of the stent are covered with no more than a single layer of the biocompatible material.Valvule cardiaque bioprothétique et procédé de fabrication de ladite valvule cardiaque bioprothétique ； le procédé consistant à : fournir : une feuille de tissu biologique (11) ； une feuille d'un matériau biocompatible (2) et un stent (4), le stent (4) ayant un bord amont (41) et un bord aval (42) ainsi qu'une surface interne et une surface externe ； fixer le tissu biologique (11) au matériau biocompatible (2) le long d'une ligne de suture (3) ； plier le matériau biocompatible pour former une structure tubulaire av
