The present invention relates to the novel opioid receptor modulators of formula (I). The invention additionally relates to what prepare such compound, containing they Pharmaceutical composition method and they treat its can pass through adjust opiate receptor improve or the disease for the treatment of in purposes.本發明涉及式(I)的新型阿片受體調節劑。本發明另外涉及用於製備這樣的化合物、含有它們的藥用組合物的方法及它們在治療其可通過調節阿片受體改善或治療的疾病中的用途。