The present invention relates to the field of human health and more particularly concerns nanoparticles for use as a therapeutic vaccine in the context of radiotherapy in a subject suffering of a cancer, in particular of a metastatic cancer or of a liquid cancer.本發明係關於人類健康領域,並且更特定言之涉及在對患癌症(特別為轉移癌或者液體癌)的個體進行放射療法的情況下作為治療疫苗之奈米顆粒。