Musc Foundation for Research Development;The Regents of the University of Colorado, a body corporate
发明人:
申请号:
EP14170690.3
公开号:
EP2826788A1
申请日:
2007.06.21
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.