A heart rate adaptive filter used in a physiology information sensing device is illustrated. The heart rate adaptive filter has a heart rate measuring device and a frequency configurable filter electrically connected to the heart rate measuring device. The heart rate measuring device can determine a heart rate or a heart rate signal according to a pulsatile signal sensed from an individual user. The frequency configurable filter can determine a transfer function thereof according to the heart rate or the heart rate signal and apply the transfer function to the pulsatile signal to generate an adaptively filtered pulsatile signal. Since the transfer function is determined according to the heart rate or the heart rate signal which has information of a characteristic frequency of the pulsatile signal, the signal-to-noise ratio of the adaptively filtered pulsatile signal can have improvement.
