GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
BEINKE, SOREN,BELYAEV, NIKOLAI NIKOLAEVICH,HESSEL, EDITH
申请号:
CA2961432
公开号:
CA2961432A1
申请日:
2015.09.22
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to methods of treating or preventing respiratory infections, in particular respiratory infections in patients with an underlying respiratory disorder such as chronic obstructive pulmonary disease (COPD). The present invention also relates to methods of treating or preventing COPD or COPD exacerbations. The invention particularly describes the role of Notch 3 and/or Notch 4 signalling in such methods and the use of Notch 3 and/or Notch 4 as therapeutic and screening targets.