Novel heterocyclic derivatives and their use in the treatment of neurological disorders

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专利权人:

NOVARTIS AG

发明人:

BADIGER SANGAMESH,CHEBROLU MURALI,HURTH KONSTANZE,JACQUIER SÉBASTIEN,LUEOEND RAINER MARTIN,MACHAUER RAINER,RUEEGER HEINRICH,TINTELNOT-BLOMLEY MARINA,VEENSTRA SIEM JACOB,VOEGTLE MARKUS

申请号：

NZ61299012

公开号：

NZ612990A

申请日:

2012.01.11

申请国别(地区):

NZ

年份:

2014

代理人:

摘要：

Disclosed herein are heterocyclic compounds of the Formula (I), in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer&rsquo；s disease or diabetes via inhibition of BACE-1 or BACE-2. In one embodiment the compound is 5-chloro-pyridine-2-carboxylic acid [6-(5-amino-3-fluoromethyl-3,6-dihydro-2H-[1,4]oxazin-3-yl)-pyridin-2-yl]-amide.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/