ВАН Лорен (US),ГРЭЙС Линда С. (US),БУКОФЗЕР Стэнли (US)
申请号:
RU2018113801
公开号:
RU2018113801A
申请日:
2016.11.11
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
Some embodiments of the present application are directed to oral formulations of L- ornithine phenylacetate and methods of using the same. These oral formulations offer alternative administration route than the standard intravenous administration of L-ornithine phenylacetate for treating hyperammonemia in patients having various acute and chronic liver diseases and disorders, for example, acute liver failure, liver cirrhosis, liver decompensation, portal hypertension, hepatic encephalopathy, or patients with urea cycle disorders.