Yan FENG;Ottavio Arancio;Shi Xian Deng;Mauro Fa;Donald W. Landry;Yitshak Francis
发明人:
Yan FENG,Mauro Fa,Ottavio Arancio,Shi Xian Deng,Donald W. Landry,Yitshak Francis
申请号:
US13493490
公开号:
US20130121919A1
申请日:
2012.06.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to a subject.