A method for immunizing a subject in need thereof against Neisseria gonorrhoeae by administering an immunogenic composition comprising one or more of the following: (i) a NHBA antigen; (ii) a fHbp antigen; (iii) a NadA antigen; (iv) a GNA1030 antigen; (v) a GNA2091 antigen; (vi) one or more of (i) to (v) above in combination with conjugated capsular saccharide from meningococcal serogroups A, C, W135 and Y.