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PHARMACEUTICAL COMPOSITION CONTAINING A TETRAHYDROFOLIC ACID
专利权人:
Bayer Pharma AG
发明人:
Kristina KING
申请号:
US13721744
公开号:
US20130178452A1
申请日:
2012.12.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to solid pharmaceutical compositions, in particular to oral contraceptives, comprising a progestogen, such as drospirenone; an estrogen, such as ethinylestradiol; a tetrahydrofolic acid or a pharmaceutically acceptable salt thereof, such as calcium 5-methyl-(6S)-tetrahydrofolate; and at least one pharmaceutical acceptable excipient or carrier. The compositions of the invention provide good stability of the tetrahydrofolic acid upon storage while still ensuring a fast and reliable release of the estrogen and the progestogen present in the composition.
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中国工程科技知识中心
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