Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases
Korea Research Institute of Chemical Technology;Katholieke Universiteit Leuven K.U. Leuven R & D
发明人:
Jung, Young Sik,Lee, Chong Kgo,Kim, Hae Soo,Jeong, Hee Chun,Kim, Pil Ho,Han, Soo Bong,Neyts, Johan,Thibaut, Hendrik Jan
申请号：
AU2012270311
公开号：
AU2012270311A1
申请日:
2012.06.18
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to a novel indanone derivative, pharmaceutically acceptable salts or optical isomers thereof, a preparation method for same, and a pharmaceutical composition containing same as an active ingredient for preventing or treating viral diseases. The indanone derivatives according to the present invention not only have low cyto-toxicity, but can also demonstrate utility as pharmaceutical compositions for preventing or treating viral diseases such as: polio, viral paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-mouth disease, blistering diseases, hepatitis A, myositis, myocarditis, pancreatitis, viral diabetes, epidemic myalgia, encephalitis, flu, herpes angina, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis, otitis media, and the like, since excellent antiviral activity against picornaviruses such as Coxsackie virus, enterovirus, echovirus, polio virus, rhinovirus, and the like, have been demonstrated.
