Rodney J. Ketner;Julian B. Lo;James A. S. Nightingale;Dwayne T. Friesen;Ravi M. Shanker;James B. West;Walter C. Babcock;William J. Curatolo
发明人:
Walter C. Babcock,William J. Curatolo,Dwayne T. Friesen,Rodney J. Ketner,Julian B. Lo,James A. S. Nightingale,Ravi M. Shanker,James B. West
申请号:
US12217700
公开号:
US08236328B2
申请日:
2008.07.08
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.