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BENZHYDROL DERIVATIVES FOR THE MANAGEMENT OF CONDITIONS RELATED TO HYPOXIA INDUCIBLE FACTORS
专利权人:
Emory University;GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION
发明人:
Binghe Wang,Erwin Van Meir,Jalisa Nicole Holmes,Stefan Kaluz,Xingyue Ji
申请号:
US15570969
公开号:
US20180289664A1
申请日:
2016.05.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
This disclosure relates to benzhydrol derivatives for managing conditions related to the Hypoxia Inducible Factor (HIF) pathway such as uses in treating cancer. In certain embodiment, the disclosure contemplates compounds and pharmaceutical compositions. In certain embodiment, the disclosure contemplates compounds disclosed herein as prodrugs, optionally substituted with one or more substituents, derivatives, or salts thereof.
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